Hey friends and fam! Hands (Amanda) here with a word or two about CBD. What is it? How does it work? Why should you try it, or not try it? Hopefully, I can have all of that answered in the next several paragraphs! Let’s do it!
So, what is CBD? CBD (Cannabidiol) is a naturally occurring compound found in the resinous flower of the cannabis plant. It is just ONE of 113 phytocannabinoids found in the cannabis plant! Despite being one of many, CBD accounts for 40% of the plants extracts. In addition, CBD accounts for one of over 80 cannabinoids in the HEMP plant. Hemp is cannabis with less than 0.3% THC, and that is because of it’s incredibly high CBD content. You go, Glen Coco!
CBD is closely related to THC, but without the psychoactive effects! CBD is even known to counteract the negative effects of THC, while still providing powerful therapeutic effects. Sounds pretty great, right? But, Hands … How does it work?
Cannabis has been used for thousands of years. We know this. But, when did we find out we had an endocannabinoid system? The development of in vitro assays for cannabinoids allowed researchers to delve deeper into how cannabinoids worked in the body. In the 1980s, findings from Allyn Howlett’s lab at St. Louis University provided solid evidence for the existence of cannabinoid receptors.
By 1988, sites of receptors were detected by radiolabeling. Using a synthesized, radiolabeled cannabinoid, Howlett’s group found that there were receptors in rat brain membranes. Two years later, in 1990, the cannabinoid 1 (CB1) receptor was cloned in both rats (U.S. National Institutes of Health) and humans (Gérard and colleagues, Brussels). It took another 3 years, in 1993, for a second cannabinoid receptor (CB2) to be cloned in Cambridge.
CB1 receptors are mainly in the central nervous system (CNS). CB2 receptors are mainly on immune cells, but have been found in the CNS when there is stress on it.
This makes CBD is a well-known treatment for a LIST of things, such as:
Auto-immune disorders (Multiple Sclerosis, Rheumatoid Arthritis, Lupus, Celiac disease, etc).
Metabolic Syndromes (diabetes, obesity)
Autism, PTSD, ADD, and even Alcohol dependence.
Crohn's, colitis, and other gut disorders.
Cardiac Disorders
Skin Diseases and Disorders (Psoriasis, dermatitis, acne, skin cancer)
Modern science has shown that the endocannabinoid system is dysregulated in nearly all pathological conditions. So, that means, we need to regulate it ourselves. (By “ourselves”, I mean those of us with dysregulated systems.) Enter CBD and THC. Both have been known to help most, if not all, conditions. Unfortunately, sometimes CBD doesn’t work by itself and you need a very small amount of THC to make it “work”. This is known as “Full-spectrum CBD”.
All CBD that I ingest (I'm seen smoking, dabbing, taking sublinguals like tinctures, edibles, etc. I do it all.), comes from the hemp plant, and is lab tested. I was recently given some Type 2 Cannabis (High CBD, low THC cannabis plant. Not hemp) as a gift, and it's a whole different lady. Refer to our interview about Moon Made Farms owner, Tina, to learn more about Type 2 cannabis.
My favorite hemp product comes from Dankdabber.com is called CBD isolate. CBD isolate is a crystalline solid or powder that contains pure CBD. CBD crystalline is surprisingly versatile when it comes to consumption. I have topped my flower bowls with it, put it under Alice’s tongue when she’s having a PNES attack, enjoy it in my coffee, and dab it!
I think I have covered it. Just about … but, if you have any questions, always feel free to send us a message!
Later! 🤟🏼
https://www.newswise.com/articles/the-discovery-of-the-endocannabinoid-system-centuries-in-the-making